Generic Name: Chlorhexidine Gluconate 0.5%
Manufacturer/Distributor: ACI Limited
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Indications of Hexisol 250 ml
For cleansing and disinfection of intact skin. Used for preoperative surgical hand disinfection, indoor hand disinfection before the aseptic operation, or after handling contaminated materials. It is used to disinfect the skin of patients before surgery or other invasive procedures.
Pharmacology
Chlorhexidine is a highly effective cationic chemopreventive agent with a broad spectrum of activity against gm + ve and gmve bacteria. Depending on its concentration, it is both bacteriostatic and bactericidal. The bactericidal effect achieved at high concentrations is due to the combination of cations with negatively charged bacterial cell walls and microbial complexes. The antibacterial effect is achieved at low concentrations, which leads to changes in the osmotic balance of bacterial cells and the leakage of potassium and phosphorus.
Dosage & Administration of Hexisol 250 ml
Pre-operative surgical hand disinfection: Dispense 5 ml of solution and spread thoroughly over both hands and forearms, rubbing vigorously. When dry apply a further 5 ml and repeat the procedure.
Antiseptic hand disinfection on the ward: Dispense 3 ml of solution and spread thoroughly over the hands and wrists rubbing vigorously until dry.
Disinfection of patient's skin: Prior to surgery apply the solution to a sterile swab and rub vigorously over the operation site for a minimum of 2 minutes. Chlorhexidine Gluconate is also used for the preparation of the skin prior to invasive procedures such as venepuncture.
Interactions of Hexisol 250 ml
Chlorhexidine is incompatible with soap and other anionic agents. Hypochlorite bleach can cause brown stains on fabrics previously exposed to chlorhexidine solutions.
Contraindications
Chlorhexidine gluconate is contraindicated in people who have previously shown hypersensitivity to chlorhexidine. However, this reaction is extremely rare.
Side Effects of Hexisol 50 ml
Irritating skin reactions occasionally occur. Systemic allergic reactions have also been reported, but are extremely rare.
Pregnancy
No untoward effects are known
Precautions
Avoid contact with the brain, meninges, middle ear, or sensitive tissues and eyes. Do not inject or use in the body cavity.
Storage Conditions
Do not store above 25° C.
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